Open for Rare

Translational Proteomics Research Unit
Director: Dr. Benoit Coulombe

Leukodystrophy - Differential Interactome Data

POLR1C N32I substitution

Differential Interactome of POLR1C-N32I

Download POLR1C-N32I Data

Disease: Hypomyelinating leukodystrophy

Target protein: POLR1C

Amino acid change: N32I

Method / Cells: FLAG AP-MS / HeLa

PubMed Reference: https://www.ncbi.nlm.nih.gov/pubmed/26151409

POLR1C N74S substitution

Differential Interactome of POLR1C-N74S

Download POLR1C-N74S Data

Disease: Hypomyelinating leukodystrophy

Target protein: POLR1C

Amino acid change: N74S

Method / Cells: FLAG AP-MS / HeLa

PubMed Reference: https://www.ncbi.nlm.nih.gov/pubmed/26151409

POLR3A R1005C substitution

Differential Interactome of POLR3A-R1005C

Disease: Hypomyelinating leukodystrophy

Target protein: POLR3A

Amino acid change: R1005C

Method / Cells: FLAG AP-MS / HEK293

Unpublished data

POLR3B R103H substitution

Differential Interactome of POLR3B-R103H

Download POLR3B-R103H Data

Disease: Hypomyelinating leukodystrophy

Target protein: POLR3B

Amino acid change: R103H

Method / Cells: FLAG AP-MS / HEK293

PubMed Reference: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587292/

POLR3B V523E substitution

Differential Interactome of POLR3B-V523E

Disease: Hypomyelinating leukodystrophy

Target protein: POLR3B

Amino acid change: V523E

Method / Cells: FLAG AP-MS / HeLa

Unpublished data